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Drug ‘Osimertinib’ provides new hope to lung cancer patients


Drug ‘Osimertinib’ provides new hope to lung cancer patients PTI Updated: June 8th, 2023, 07:20 IST in International , Sci-Tech 0 Share on Facebook Share on Twitter Share on WhatsApp Share on Linkedin New Delhi: A once-daily pill halved people’s risk of dying from a common lung cancer when they took the drug after tumour-removal surgery, trial results from a global study has proved. The research has been published recently in ‘The New England Journal of Medicine’. It states that taking the drug ‘Osimertinib’ after surgery dramatically reduced the risk of patients dying by 51 per cent.

The researchers randomly assigned eligible patients in a 1:1 ratio to receive Osimertinib (80mg once daily) or placebo until disease recurrence was observed. Of 682 patients who underwent randomisation, 339 received ‘Osimertinib’ also known as ‘Tagrisso’ and made by AstraZeneca, and 343 received placebo. In the primary analysis population, an estimated 85 per cent of patients treated with Osimertinib were alive at five years compared to 73 per cent on placebo, the researchers said.

In the overall trial population, an estimated 88 per cent of patients treated with ‘Osimertinib’ were alive at five years compared to 78 per cent on placebo, they said. The study found that ‘Osimertinib’ reduced the risk of death by 51 per cent compared to placebo in both the primary analysis population, the researchers said. “These highly anticipated overall survival results, with 88 per cent of patients alive at five years, are a momentous achievement in the treatment of early-stage EGFR-mutated lung cancer,” said principal investigator in the trial, Roy S Herbst, Deputy Director and Chief of Medical Oncology at Yale Cancer Centre and Smilow Cancer Hospital, US.

“These data underscore that adjuvant treatment with ‘Osimertinib’ provides patients with the best chance of long-term survival,” Herbst said. Susan Galbraith, executive vice-president, Oncology R&D, AstraZeneca, said ‘Osimertinib’ cut the risk of death by more than half in the adjuvant setting, further establishing this transformative medicine as the backbone treatment for epidermal growth factor receptor (EGFR)-mutated lung cancer. “These results emphasise the importance of diagnosing patients with lung cancer early, testing for EGFR mutations and treating all those with an EGFR mutation with Tagrisso (Osimertinib),” Galbraith said.

The trial results were presented Monday during the Plenary Session at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago Tags: AstraZeneca cancer death drug lung Osimertinib Share Tweet Send Share Suggest A Correction Enter your email to get our daily news in your inbox. Leave this field empty if you’re human: Related Posts Imran Khan gets booked under anti-terrorism law in Supreme Court lawyer’s murder case June 7, 2023 President Droupadi Murmu arrives in Serbia on state visit June 7, 2023 Greece seeks assistance from rival Turkiye over migration spike along border river June 7, 2023 Odisha train tragedy: British Parliament motion conveys condolences June 7, 2023 AI outperforms standard risk model for predicting breast cancer: Study June 7, 2023 Generative AI transforming businesses at rapid pace: Survey June 7, 2023 Leave a Reply Cancel reply Your email address will not be published. Required fields are marked * Comment * Name * Email * Website Save my name, email, and website in this browser for the next time I comment.


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